19 research outputs found

    Face Recognition Via GroupWise Registration Method

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    One of the important research area in image processing is face recognition. We introduce a new framework for tackling face recognition problem. Here propose a new way technique of face recognition problem, which is formulated as group wise deformable image registration and feature matching. The main contributions of the proposed method is to suppresses image noise without reducing the image sharpness we will use Median filtering, Each pixel in a facial image is represented by an anatomical signature obtained from its corresponding most salient scale local region Based on the anatomical signature calculated from each pixel, a novel Markov random field based group wise registration framework is proposed to formulate the face recognition problem. DOI: 10.17762/ijritcc2321-8169.150317

    Head and trunk kinematics and kinetics in normal and cerebral palsy gait: a systematic review.

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    Background: Cerebral palsy (CP) is a neuromuscular disability characterised by a persistent disorder of movement and posture due to a non-progressive lesion in a developing brain. In children with CP, gait is compromised in a variety of ways. A number of studies have suggested that there is a higher degree of biomechanical variations including kinematics and kinetics at head and trunk while analysing a CP gait. Since coordinated movements of head and trunk are important to analyse a typical gait, it is important to determine these biomechanical changes among children with CP for altered movements such as decreased head and trunk stability. Studies have also reported a variety of outcome measures for clinical use. However, the results among the studies are not consistent as there is variability for altered biomechanics based on type and level of the disorder which requires further investigation. Although clinically very useful, the data regarding the head and trunk biomechanics in children with CP is limited. In this study, a systematic review was done to determine the head and trunk kinematic and kinetics variations in CP gait compared to TD children of the same age-group. Methodology: Scientific articles were obtained by a search in databases including Science Direct, Cinahl, Springer Link, Sport discuss, Web of Science and Pubmed. Limitations used were AND/OR. Full-text articles from 1999 to 2017 in English were selected. Results: A total of 3029 records were identified that included Science Direct (n=1854), Cinahl (n=176), Springer Link (n=121), Sports Discuss (n=101), Web of Science (n=14) and Pubmed (n=763). After removing the duplicates, 1786 records were obtained. Fifty-one full text articles were selected for the eligibility and 27 were included in the study. Conclusions: In this review study, we conclude that children with CP have a significant difference in head and trunk kinetics and kinematics compared to age-matched TD children

    Kinetics and kinematics of diabetic foot in type 2 diabetes mellitus with and without peripheral neuropathy: a systematic review and meta-analysis.

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    Diabetes mellitus patients are at increased risk of developing diabetic foot with peripheral neuropathy, vascular and musculoskeletal complications. Problems develop with a relatively high risk of infection, gangrene and amputation. In addition, altered plantar pressure distribution is an important etiopathogenic risk factor for the development of foot ulcers. The purpose of this systematic review is to understand the biomechanical changes involved through studies of foot kinematic and kinetic in type 2 diabetes mellitus. Scientific articles were identified using electronic databases including Science Direct, CINAHL, Springer Link, Medline, Web of Science, and Pubmed. The selection of articles to include in the systematic review was narrorwed after reading the full text, focusing on studies that used experimental designs relating to the biomechanics of diabetic foot. The meta-analysis report on gait velocity (neuropathy = 128 and non-diabetes = 131) showed that there was a significantly lower gait velocity in neuropathy participants compared to non-diabetes age-matched participants at a high effect level (-0.09, 95% CI -0.13 to 0.05; p < 0.0001). Regarding knee-joint flexion range, there was a significant difference between neuropathy and non-diabetes groups (4.75, 95% CI, -7.53 to 1.97, p = 0.0008). The systematic review found significant differences in kinematic and kinetic variables among diabetic with neuropathy, diabetic without neuropathy and non-diabetic individuals. The review also found that the sample sizes used in some studies were not statistically significant enough contribute reliably to the meta-analysis, so further studies with higher sample sizes are required

    A simple method for deprotection of <i>tert</i>-butyldimethylsilyl ethers by using stannous chloride under microwave irradiation

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    322-324A facile regeneration of hydroxy compounds from their tert-butyldimethylsilyl ethers in presence of stannous chloride under solvent free conditions using domestic microwave oven has been performed efficiently in a short period (5-6 min). The conversion using stannous chloride in ethanol or water for comparison of the efficiency has been described. The generality of the transformation has been confirmed by several examples

    Association of glycaemic control with demographics, diabetes management information and body fat composition in persons with type 2 diabetes mellitus (T2DM): a need for multi-disciplinary management

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    Type 2 diabetes mellitus (T2DM) is a chronic condition that can cause complications due to poor glycaemic control. The demographic characteristics, information related to DM and management, anthropometric variables, and the body fat composition of T2DM individuals are important factors influencing glycaemic control. This study was conducted to explore the association between glycaemic control and selected demographic characteristics, information on T2DM management, and body fat composition in T2DM patients. This cross-sectional survey amongst people with T2DM was conducted in the Udupi district of South India. A number of 467 participants were selected for the study using a simple random sampling technique. The survey included three parts: a questionnaire, an anthropometric and body fat composition measurement, and a biochemical assessment. The multivariate logistic regression model showed that not consulting the dietician (OR=6.074); the presence of complications (OR=2.955); visceral fat ≥10 (OR=2.037); non-compliance to exercise (OR=2.007); availing treatment from the private sector (OR=1.85); and non-consumption of traditional remedies (OR=1.651) were the associated factors to poor glycaemic control in T2DM patients. Not consulting dieticians, complications, non-compliance to exercise, not consuming traditional remedies, visceral fat ≥10 and availing treatment at private setup were the significant associated factors for the poor glycemic control. </p

    Synthesis and evaluation of 4/5-hydroxy-2,3-diaryl(substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anticancer agents

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    A new series of 2,3-diaryl-4/5-hydroxy-cyclopent-2-en-1-one analogues replacing the cis double bond of combretastatin A-4 (CA-4) by 4/5-hydroxy cyclopentenone moieties was designed and synthesized. The analogues displayed potent cytotoxic activity (IC50 &#60; 1 &#956;g/mL) against a panel of human cancer cell lines and endothelial cells. The most potent analogues 11 and 42 belonging to the 5-hydroxy cyclopentenone class were further evaluated for their mechanism of action. Both of the analogues led to cell cycle arrest at G2/M phase and induced apoptosis in endothelial cells. Antitubulin property of 42 was superior to 11 and comparable to CA-4. The compound 42 had better aqueous solubility, metabolic stability, and pharmacokinetic profile than CA-4 and also demonstrated significant tumor regression in the human colon xenograft model. Our data suggests that cis-restricted analogues of CA-4 are a new class of molecules that have the potential to be developed as novel agents for the treatment of cancer
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